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Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
doi: 10.1016/j.scitotenv.2021.146264 145 XiaYLanYXuYLiuFChenXLuoJet al
Brand: DR.DAVEY Item NO.: DV-6833 Shantou S.E.Z Baojie Industrial Co., Ltd
Glutathione supplements formulated with vitamin C are widely chosen because vitamin C supports antioxidant activity and helps maintain glutathione levels in the body
This finding highlights not only the key role that mitochondrial metabolism has in modulating response and resistance to TS inhibitors, but the wider opportunity afforded to enhance TS inhibitor-mediated anti-cancer effects by targeting mitochondrial metabolism using metformin or other compounds with similar mitochondrial impact
When acetaminophen use is unavoidable, proactive support of glutathione and detox pathways is essential
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